Which tissue type is firm with no compressibility?

• A. Neoplastic tissue
• B. Normal glandular tissue
• C. Fat
• D. Cystic lesion

Answer: (A)

Tissue stiffness and compressibility are key clues in differentiating breast lesions on ultrasound. A lesion described as firm with no compressibility signals a very stiff mass, which is characteristic of neoplastic tissue. Malignant and many benign neoplasms tend to have increased cellularity and fibrous stroma that resist deformation, so they feel solid and unyielding when the transducer applies pressure.

Fat, on the other hand, is soft and easily compressible, so it does not feel non‑compressible. Cystic lesions are fluid-filled and typically compressible as well, often showing posterior acoustic features related to fluid content. Normal glandular tissue can be denser than fat, but it does not usually present as completely non‑compressible.

So the description of a firm, non‑compressible tissue aligns best with neoplastic tissue, which is why that option fits.