Which statement about fibroadenoma is true?

• A. Estrogen does not influence its growth
• B. It occurs only in postmenopausal women
• C. It is estrogen-induced tumor
• D. It always regresses after puberty

Answer: (C)

Fibroadenoma is a benign breast lesion that is influenced by estrogen. Estrogen stimulates the glandular and stromal components of the lesion, so its size can increase during periods of higher estrogen—such as pregnancy or when taking estrogen-containing medications—and often decreases after menopause when estrogen levels fall. This hormone responsiveness is why describing it as estrogen-induced best fits its behavior. It does not occur only in postmenopausal women; in fact, it is most common in younger, reproductive-age women. It doesn’t always regress after puberty, and while some lesions may shrink with aging, others may persist or change with hormonal fluctuations. Estrogen’s role in growth is the key concept here.